For perks, I would recommend Quick Revive for Danu, Stamin-Up for Ra, Dying Wish for Zeus, and Deadshot Dealer for Odin. Before starting the game, I would recommend if you are playing solo, to use the Hammer or Chakram special weapon, and if you are in co-op, I would recommend everyone use the Sceptre of Ra, because being able to revive others with the staff and let them keep their perks is a huge help.